A fMRI Study of Cortical Reorganization in Chronic Stroke Hemiplegia Treated with Constraint-induced Movement Therapy
- VernacularTitle:脑卒中患者强制性使用运动治疗的fMRI研究
- Author:
Bo WEN
;
Lin MA
;
Changshui WENG
;
Zhixin ZHENG
;
Tong XIN
- Publication Type:Journal Article
- Keywords:
stroke, constraint-induced movement therapy, functional reorganization
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(4):366-367
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the evidence of cortical reorganization in stroke hemiplegia treated with constraint-induced movement therapy(CIMT)by fMRI.Methods Five patients with chronic stroke were evaluated with the Action Research Arm Test(ARAT).The functional MRI(fMRI)was performed on a 3.0-T MRI with echo-planar imaging.The subjects were required to finish the finger-tapping task and undergo fMRI before and after CIMT.A block design was used for the inspection.Results After CIMT,the function of upper limb(sick side)of patients improved significantly assessed by ARAT(P<0.001),and cortical reorganization was found on fMRI.Conclusion CIMT can improve motor function of upper limb of chronic stroke patients with hemiplegia and induce cortical reorganization as measured by fMRI.
