Suitable Dose and Correlation Factors in Treatment of Spastic Cerebral Palsy by Botulinum Toxic A Block
- VernacularTitle:A型肉毒毒素缓解脑瘫痉挛的适宜剂量与相关因素的研究
- Author:
Jianjun LIU
;
Shurong JI
;
Yingyuan HU
;
Weihong WU
;
Yanchun LI
;
Huabao LU
;
Yan ZHANG
- Publication Type:Journal Article
- Keywords:
cerebral palsy, spasticity, botulinum toxic A, nerve block, dose
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(4):358-360
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the optimal dose of botulinum toxic A(BTX-A)for releasing spasticity of cerebral palsy(CP)and related factors.Methods 39 children with CP was treated by BTX-A injected in local muscles to release the spasticity.Results After treatment,23 children had good curative effect.In them,15 cases were male,8 cases were female,the mean age was 60.7±26.9 months(range 33 to 145 months).There was no correlation between the optimal unit dose of BTX-A and those including sex,age,body weight,diagnosis type,degree of Gross Motor Function Classification System(GMFCS),etiological factor and the injections.There was a linear positive correlation between the optimal unit dose of BTX-A and the score of Modified Ashworth Scale(MAS).Conclusion BTX-A can release the spasticity of CP children,the injecting dose is correlated with MAS score.
