Research progress of imaging flow cytometry in automatic analysis of radiation biodosimetric indicators
- VernacularTitle:成像流式细胞术在辐射生物剂量学指标自动分析中的研究进展
- Author:
Xiaoming LIU
1
;
Jiao CHENG
1
;
Shuangshuang CUI
1
;
Xuhong DANG
1
;
Juancong DONG
1
Author Information
- Publication Type:Journal Article
- Keywords: Biological dose estimation; Imaging flow cytometry; Automation; Nuclear emergency
- From: Chinese Journal of Radiological Health 2023;32(1):62-65
- CountryChina
- Language:Chinese
- Abstract: A large number of people would be exposed to irradiation in large-scale nuclear and radiation accidents or nuclear terrorist attacks. Therefore, it is urgent to establish rapid and high-throughput biodosimetry for in triage, providing a basis for emergency management. Imaging flow cytometry (IFC) possesses the high through put advantages of traditional flow cytometry and the sensitivity and specificity of microscope, and has a good application prospect in the research and development of rapid, automated, and high-throughput biological dose estimation technology. This article reviews the application progress of IFC in biodosimetry, and provides a reference for the development of biological dose estimation and detection equipment for large-scale nuclear and radiation accidents.