Progress of research on application of chondroitin sulfate in osteogenic repair materials
10.13591/j.cnki.kqyx.2023.01.015
- VernacularTitle:硫酸软骨素应用于骨修复材料中的研究进展
- Author:
Qian ZHANG
;
Chang WANG
;
Chen LIANG
;
Xingyuan QU
;
Yue LIU
;
Baojun YAN
;
Lei WANG
- Publication Type:Review
- Keywords:
chondroitin sulfate;
bone regeneration;
osteogenesis;
bone tissue engineering
- From:
STOMATOLOGY
2023;43(1):88-91
- CountryChina
- Language:Chinese
-
Abstract:
Chondroitin sulfate is an important component of extracellular matrix (ECM) in animal and human body. In recent years, chondroitin sulfate has been proven to have potential efficacy in biomedical application and has been widely used in bone regeneration and osteogenesis, especially in craniofacial reconstruction and dental medicine. Research shows that chondroitin sulfate derivatives and chondroitin sulfate composite scaffolds have great potential in promoting osteogenesis and biomineralization. However, due to the variety of chondroitin sulfate and various application forms, study on its mechanism of osteogenic repair is still insufficient. In this paper, biological characteristics, bone regeneration and osteogenesis of chondroitin sulfate, its application in different biomaterial design and future prospect are discussed.
