Application of Perphenazine to Treat Psychotic Symptoms of Senile Dementia:31 Case Report
- VernacularTitle:小剂量奋乃静治疗老年痴呆精神病性症状的临床观察
- Author:
Yingjuan SHI
;
Feng WANG
;
Minhui HE
- Publication Type:Journal Article
- Keywords:
perphenazine, senile, dementia, psychotic symptoms
- From:
Chinese Journal of Rehabilitation Theory and Practice
2008;14(3):286-286
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of small dosage of perphenazine(2~6 mg)on psychotic symptoms of senile dementia.Methods 31 senile cases with psychotic symptoms after dementia(Alzheimer disease or vascular dementia)accepted small dosage of perphenazine in addition of the conventional therapy.They were assessed with Sadoz Clinical Assessment Geriatric(SCAG)and Treatment Emergent Symptom Scale(TESS).Results The score decreased 50%~75%(markedly improved)in 2 cases,25%~50%(improved)in 22 cases,lower than 25%(no improved)in 7 cases.Some mild emergent symptoms have been observed.Conclusion Small dosage of perphenazine is safe and effective in treating psychotic symptoms of senile dementia.