Effect of Fluoxetine on Depression Neurologic Impairment and Activity of Daily Living after Cerebral Infarction
- VernacularTitle:氟西汀对脑梗死后抑郁患者神经功能缺损及日常生活能力的影响
- Author:
Luping FAN
;
Xiaoguo YANG
;
Yijun LIN
;
Xiaoding CHEN
;
Youchao ZHANG
- Publication Type:Journal Article
- Keywords:
fluoxetine, cerebral infarction, depression, activity of daily living
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(6):585-586
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of fluoxetine on the depression neurologic impairment and activity of daily living after cerebral infarction.Methods 80 patients with acute cerebral infarction following depression were randomly divided into treatment group and control group, 40 cases in each group. Two groups were assessed with Modified Edinburgh-Scandinavia Stroke Scale(MESSS), Hamilton Depression Scale(HAMD) and Modified Barthel Index(MBI) before and after treatment.Results There were no significant difference between the two groups before treatment in HAMD, MESSS and MBI（P＞0.05）, while there were significantly different between the two groups in HAMD, MESSS and MBI 6 weeks after treatment（P＜0.01）. Conclusion Fluoxetine can alleviate depression of patients with acute cerebral infarction and improve the symptom of neurological function and the activity of daily living.
