Epidemiological characteristics of measles cases with immunization history of MCV in Liaoning in 2014-2021
10.3969/j.issn.1006-2483.2023.02.007
- VernacularTitle:2014—2021年辽宁省麻疹病例免疫史特征分析
- Author:
Xiaohui AN
1
;
Wensi WANG
1
;
Xing FANG
1
Author Information
1. Department of National Immunization Program , Liaoning Provincial Center for Disease Control and Prevention, Shenyang , Liaoning 110005 , China
- Publication Type:Journal Article
- Keywords:
Measles cases;
Immunization history;
Epidemiological characteristics
- From:
Journal of Public Health and Preventive Medicine
2023;34(2):32-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the epidemiological characteristics of measles cases with immunization history of measles-containing vaccine (MCV), and to provide a basis for improving measles prevention and control measures. Methods Data were collected through the measles surveillance system and the immunization program information management system. Data were analyzed by descriptive epidemiological methods. Results A total of 9 164 cases of measles were reported in Liaoning Province during 2014-2021, of which the cases of measles with immunization history of 1 dose MCV accounted for 5.64%, and ≥ 2 doses accounted for 3.60%. There was a statistically significant difference in the immunization proportion among different years (χ2=184.534, P<0.001). The cumulative inoculation rate of measles cases was 23.85%, the immunization rates among different groups varied from 3.57% to 35.94%, and the differences were statistically significant (χ2=109.448, P<0.001). There was a statistically significant difference between 2-6 years old and 7-14 years old in the immunization rate of 1 dose and ≥ 2 doses (χ2=4.147, P<0.05). The onset time of most cases was over 2 weeks after the last dose of MCV vaccination, accounting for 82.06%. The incidence rates of fever, cough, catarrh symptoms, conjunctivitis, lymph node enlargement and articular pain were all significantly lower in the cases with immunization history than those in the patients without a history of MCV immunization (P<0.05). Conclusion The cases with immunization history account for a certain proportion in measles cases, mainly secondary vaccination failure. The incidence rate of fever, cough, catarrhal symptoms, conjunctivitis, Koch's patches, lymphadenopathy, joint pain, and other clinical symptoms in measles patients with a history of MCV immunization is lower than that in patients without immunization history. Inoculation of MCV is of great significance in relieving clinical symptoms. It is necessary to inoculate two doses of MCV in time for measles prevention and control.
