Effects of Hyperbaric Oxygen on Serum Adhesion Molecules in Acute Intracerebral Hemorrhage
- VernacularTitle:高压氧对脑出血患者血清黏附分子的影响
- Author:
Shengli LI
;
Xiangyang ZHU
;
Zhengxie DONG
;
Yong ZHOU
;
Jia LI
;
Huaiyu HUANG
- Publication Type:Journal Article
- Keywords:
hyperbaric oxygen, intracerebral hemorrhage, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), E-selectin
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(5):468-469
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of hyperbaric oxygen （HBO） therapy in patients with acute intracerebral hemorrhage on serum adhesion molecules. Methods 66 cases with acute intracerebral hemorrhage were divided into routine treatment group (n=33) and HBO treatment group (n=33). 30 health persons were selected as normal trontrol. The level of adhesion molecules, including intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin, were measured before and after treatment. Results The levels of adhesion molecules in routine and HBO treatment groups were higher than those in normal control group when hospitalized (P<0.01). All the adhesion molecules levels in two treatment group were decreased after the treatment, and more significantly in HBO group (P<0.05). Conclusion HBO therapy may ameliorate the adhesion molecule abnormalities after intracerebral hemorrhage.
