Multifocal Electroretinography in Retinitis Pigmentosa With Non-recordable Full-field Electroretinography.
10.3341/jkos.2009.50.12.1817
- Author:
Sun Young JANG
1
;
Sang Hyun LIM
;
Young Hoon OHN
Author Information
1. Department of Ophthalmology, Soonchunhyang University, College of Medicine, Bucheon, Korea. yhohn@schbc.ac.kr
- Publication Type:Original Article
- Keywords:
Multifocal electroretinography (mfERG);
Retinitis pigmentosa
- MeSH:
Electroretinography;
Eye;
Humans;
Retinaldehyde;
Retinitis;
Retinitis Pigmentosa;
Retrospective Studies;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2009;50(12):1817-1823
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the clinical potential of multifocal electroretinography (mf-ERG) for the evaluation of residual retinal function in retinitis pigmentosa (RP). METHODS: From a group of 41 patients with RP examined for full-field and mf-ERGs, 24 patients were selected in whom the full-field ERGs were non-detectable. Data from the mf-ERGs of this group were reviewed retrospectively. Patients were divided into two groups based on best corrected visual acuity (BCVA); Group A, with a BCVA of less than 0.5, and group B with a BCVA greater than 0.5. The amplitudes and implicit times of Ring 1 and Ring 2 among six concentric rings were measured for comparison between mf-ERG groups. RESULTS: In the mf-ERGs, the amplitudes of Ring 1 and Ring 2 were reduced and implicit time was delayed in all 48 eyes of 24 patients in whom scotopic and photopic responses were non-detectable in full-field ERGs, whereas, there were no detectable responses in Rings 3 thru 6. There was a greater reduction in amplitude and an increased delay in implicit time in group A. CONCLUSIONS: The mf-ERG can estimate the residual macular function in a group of patients with RP in whom the full-field ERG is non-recordable.
