Effects of Danshen Shujingwan on Cervical Spinal Cord Compression in Rats
- VernacularTitle:丹参舒颈丸对颈髓受压模型大鼠病理变化的影响
- Author:
Wei TIAN
;
Lan SUN
;
Zhengmei WANG
;
Yuhui ZHANG
;
Yongqing ZHAO
- Publication Type:Journal Article
- Keywords:
spinal cord injury, pathology, Danshen Shujingwan, rat
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(5):436-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Danshen Shujingwan on cervical cord compression in rats. Methods 60 healthy male SD rats of 8 weeks old were randomly divided into 6 groups: sham group (N group), model group (M group), DSW groups of high, medium and low dosages, and group treated with Jingfukang (J group), with 10 rats in each. The cervical cord compression models were established by transplanted silica gel. From 7 d after model establishments, the rats were respectively treated with drug by gavage for 30 d. They were observed pathologically. Results The extent and scope of damage were less in the treatment groups than in the model group (P<0.001), while the number of normal neurons remained more in the treatment groups (P<0.01).Conclusion DSW can decrease the damage after cervical spinal cord compression, protect the neurons from injuring.
