Highlights of human uterus transplantation
10.3969/j.issn.1674-7445.2023.02.019
- VernacularTitle:人体子宫移植相关要点讨论
- Author:
Yu LIU
1
;
Yan DING
;
Xuyin ZHANG
;
Keqin HUA
Author Information
1. Department of Gynecological Oncology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200090, China
- Publication Type:Research Article
- Keywords:
Uterus transplantation;
Donor selection;
Uterine vessel;
Immunosuppressive therapy;
Complication;
Uterine vitality;
Pregnancy;
Live birth
- From:
Organ Transplantation
2023;14(2):305-
- CountryChina
- Language:Chinese
-
Abstract:
As a novel solid organ transplantation, uterus transplantation has become an important approach for women with uterine infertility to obtain biological offspring. Multiple technological challenges exist in uterus transplantation, such as acquisition of vascular pedicle, organ perfusion and vascular suture, etc. However, with the development and application of uterus transplantation in animal model and transplantation in human cadavers, a lot of problems have become new hot topics of discussion, such as the selection of uterus transplantation donors and recipients, selection of uterine vessels, prevention and treatment of complications after uterus transplantation, evaluation of graft vitality, timing of pregnancy and delivery, timing of hysterectomy, mental health of donors and recipients and offspring health, etc. According to current data and outcomes of human uterus transplantation worldwide, these hot topics were reviewed in this article, aiming to provide reference for promoting the development and progress of human uterus transplantation research in China.
