Double Trouble: A case of synchronous high-grade serous carcinoma of the fallopian tube and borderline mucinous tumor of the ovary
- Author:
Christopher John Jericho A. Balicanta
1
;
Jean Anne B. Toral
1
Author Information
- Publication Type:Case Reports
- Keywords: Borderline mucinous tumor of the ovary; Fallopian tube carcinoma; High‑grade serous carcinoma; Synchronous primary malignancies
- MeSH: Fallopian Tubes; Fallopian Tube Neoplasms; Neoplasms, Cystic, Mucinous, and Serous
- From: Philippine Journal of Obstetrics and Gynecology 2022;46(5):218-223
- CountryPhilippines
- Language:English
- Abstract: A 55‑year‑old, Gravida 2 Para 2 (2002), presented with postmenopausal vaginal bleeding. Workups pointed toward ovarian malignancy with distant metastasis (pleural effusion). Exploratory laparotomy, bilateral salpingo‑oophorectomy, surgical staging, and appendectomy were performed. On histopathological examination, synchronous high‑grade serous carcinoma of the right fallopian tube and borderline mucinous tumor of the left ovary were diagnosed. Primary fallopian tube carcinomas are very uncommon, while synchronous tumors of the female genital tract are extremely rare. Furthermore, there is a paucity of literature discussing the occurrence of synchronous primary malignancies arising from the fallopian tube and the ovary. It is crucial to differentiate primary malignancies from metastatic cancers to determine accurate staging and prognosis, as well as to assign appropriate treatment strategies. Immunohistochemistry and molecular testing play vital roles as adjunctive diagnostic tools to histologic examination in determining the origins of these tumors and distinguishing primary tumors from metastasis.
- Full text:PhilippJObstetGynecol465218-2427324_004027.pdf