Characteristics of COVID-19 positive pregnant patients admitted in a private tertiary hospital and their maternal and neonatal outcomes
- Author:
Josephine Alexandra D. Lim
1
;
Zarinah G. Gonzaga
1
;
Mariles R. Hernandez‑Nazal
1
Author Information
- Publication Type:Journal Article
- Keywords: Obstetric
- MeSH: Respiratory Distress Syndrome; Cesarean Section; Coronavirus; COVID-19; Intensive Care Units, Neonatal; Pandemics; Pregnant Women; SARS-CoV-2
- From: Philippine Journal of Obstetrics and Gynecology 2022;46(2):69-79
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:The severe acute respiratory syndrome coronavirus 2 pandemic has had profound effects globally. Historical experience with previous Coronaviruses has shown increased maternal and perinatal morbidity and mortality, theoretically secondary to the physiologic changes of pregnancy. As of August 2021, the Philippines is the 23rd top country worldwide in terms of total number of cases, yet there remains to be a sparse pool of information both internationally and locally
Objectives:This study aims to present the prevalence, clinical characteristics, as well as the neonatal, obstetric, and maternal outcomes of all pregnant women admitted in the institution who had active or previous COVID‑19 infection
Methodology:Retrospective review of data using the hospital’s health information system was utilized. Within the study period, all admitted obstetric patients who had at least one positive result in a RT‑PCR naso‑oropharyngeal swab for SARS‑CoV‑2 were included in this study and categorized into: (1) symptomatic, (2) recovered, and (3) asymptomatic
Results:A total of 48 patients were included in the study, where prevalence of COVID‑19 in pregnancy was 3.65%. Results showed that most patients were in the third trimester, and contrary to the non‑pregnant population, majority (60.41%) did not have comorbidities. Most remained asymptomatic (33.33%) or had mild symptoms (18.75%), and underwent abdominal delivery (50%) for obstetric indications. COVID‑19 status was not associated with adverse obstetric outcomes in this study population, but had significant association with preterm birth (p=0.019) and NICU admission (P=<0.001
Conclusion:Overall, most cases were asymptomatic and had good prognosis even with the adaptations a pregnant woman undergoes. In addition, neonatal outcomes were generally good regardless of the association with preterm birth and NICU admission. Lastly, there was no appreciated evidence for vertical transmission - Full text:PhilippJObstetGynecol46269-2711644_073156.pdf