Co-infection with cryptococcal meningitis and Japanese encephalitis in an immunocompetent patient: A case report.
- Author:
Golden Tamon-Gayo
1
;
Randolf Fangonilo
2
Author Information
- Publication Type:Case Reports
- Keywords: Co-infection; Cryptococcal Meningitis
- MeSH: Meningitis, Cryptococcal; Encephalitis, Japanese
- From: Philippine Journal of Neurology 2022;25(2):17-20
- CountryPhilippines
- Language:English
- Abstract: Cryptococcal meningitis is a severe infection in both immunocompetent and immunosuppressed hosts. This report is an unusual case of co-infection with cryptococcal meningitis and Japanese encephalitis in a seronegative human immunodeficiency virus patient. A 51-year-old human immunodeficiency virus-negative patient presented with high-grade fever, nausea, vomiting, and later on, behavioral changes. A lumbar puncture was performed and cerebrospinal fluid revealed the presence of Cryptococcus and Japanese encephalitis virus. Treatment commenced with intravenous amphotericin B and flucytosine. Her condition initially improved but later on deteriorated due to bacteremia (MRSA-mecA gene positive) and septic shock which resulted in the patient’s demise. The occurrence of this co-infection in the absence of HIV infection is rare and there was no documented case up to this date.
- Full text:Co-infection with cryptococcal meningitis.pdf