Synchronous Endometrioid Endometrial and Serous Ovarian Carcinoma: A double gynecologic jeopardy
- Author:
Ana Victoria C. Crimen
1
;
Nora A. Martin
1
;
Maria Kathrina S. Marinas
1
Author Information
- Publication Type:Case Reports
- Keywords: Endometrioid endometrial carcinoma; Serous ovarian carcinoma; Synchronous malignant tumors; Wilm’s tumor 1
- MeSH: Vimentin
- From: Philippine Journal of Obstetrics and Gynecology 2021;45(5):204-209
- CountryPhilippines
- Language:English
- Abstract: Synchronous malignant tumors are two primary tumors diagnosed at the same time during surgery. A postmenopausal, nulligravid, presented with vaginal bleeding. Ultrasound revealed an endometrial and right ovarian mass, both with nonbenign features. Cancer Antigen 125 and Human Epididymis Protein 4 were elevated. She underwent extrafascial hysterectomy with bilateral salpingo-oophorectomy with the frozen section of the endometrium and right ovary, followed by complete surgical staging. Histopathology report was endometrioid endometrial carcinoma and high-grade serous ovarian carcinoma. The endometrial and ovarian tissues tested positive for vimentin and Wilm's Tumor 1 (WT1), respectively, suggesting both are primary independent tumors. The pelvic lymph nodes and recto-sigmoid lymph nodes tested positive for vimentin and negative for WT1, suggesting endometrial tumor metastasis. The final diagnosis is synchronous endometrioid endometrial carcinoma Stage IIIC1 and high-grade serous ovarian carcinoma Stage IA, right ovary.
- Full text:PhilippJObstetGynecol455204-1963394_052713.pdf
