Research advances in myosteatosis in chronic liver diseases
10.3969/j.issn.1001-5256.2023.02.031
- VernacularTitle:慢性肝病并发肌肉脂肪变性的研究进展
- Author:
Jintao SUN
1
;
Fengxia LI
1
Author Information
1. Department of Gastroenterology, The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan 030012, China
- Publication Type:Review
- Keywords:
Liver Diseases;
Malnutrition;
Myosteatosis;
Pathological Conditions, Signs and Symptoms
- From:
Journal of Clinical Hepatology
2023;39(2):444-449
- CountryChina
- Language:Chinese
-
Abstract:
Myosteatosis is the main manifestation of malnutrition and is a common complication of chronic liver diseases, with a negative impact on the progression and prognosis of liver diseases. There is no gold standard for the diagnosis of myosteatosis, and CT is a commonly used diagnostic method. Myosteatosis in chronic liver diseases has diverse mechanisms, and hyperammonemia, increased cathepsin D level in circulation, insulin resistance, mitochondrial dysfunction, and chronic systemic microinflammation play an important role in myosteatosis. Early intervention of these factors can improve prognosis. With reference to related studies in China and globally, this article reviews the features, diagnostic methods, pathogenesis, treatment, and intervention of myosteatosis.
