30 Children with Hand Foot and Mouth Disease following Acute Flaccid Paralysis
- VernacularTitle:手足口病并发急性弛缓性麻痹30例临床分析
- Author:
Jing LIU
;
Ruping LUO
;
Nan HU
;
Junying WANG
;
Xiangmei LIU
- Publication Type:Journal Article
- Keywords:
hand foot and mouth disease, acute flaccid paralysis, clinical manifestation
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(12):1190-1191
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the clinical characteristics and epidemic analysis in children with hand foot and mouth disease(HFMD) following acute flaccid paralysis(AFP).Methods30 children with HFMD following AFP in Hunan Province Children's Hospital were surveyed retrospectively.ResultsAll the patients were below 5 years old, 83.34％ were 1～3 years old, 90% from countryside. Besides AFP of limbs, 86.67% complicated with encephalitis. The major clinical characteristics as followed: fever(100.00%), skin rash(100.00%), startle and skip(80.00%), emesis(63.33%), neurogenic pulmonary edema(13.33%) and urinary retention(16.67%). The most palsy occurred in 3～5 days after onset, and the palsy in lower limbs was major, only a few had palsy in upper extremities or tetraplegia. 26 cases were infected with enterovirus type 71(EV 71), 1 case infected other EV, 3 cases were negatively. The EMG showed that the amplitude of active potential lowered in the femoral nervus, tibial nerve, peroneal nerve, axillay nerve and musculocutaneous nerve, or/and the motor conduction velocity slowed down, the damage of proximate nerve was the most common.ConclusionThe most children with HFMD following AFP were infected with EV 71. Encephalitis was the common complication. The symptom of EV 71 was more severious than distribute EV.
