Genitourinary Dysfunction in Multiple System Atrophy: 5 Case Report
- VernacularTitle:多系统萎缩的泌尿生殖系功能障碍5例报道
- Author:
Yang HU
;
Limin LIAO
;
Yanhe JU
;
Guang FU
;
Juan WU
- Publication Type:Journal Article
- Keywords:
multiple system atrophy, genitourinary dysfunction, videourodynamics
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(12):1127-1130
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo recognize the features of genitourinary dysfunction in multiple system atrophy (MSA) and the importance of videourodynamics.Methods5 cases of MSA were reviewed.ResultsGenitourinary dysfunction in MSA included voiding problem, nocturnal urinary frequency, urgency, impotence and so on. The characteristic appearance of videourodynamics was that postvoiding volume more than 100 ml, detrusor-external sphincter dyssynergia (DESD) and open bladder neck at the start of bladder filling. The abnormal sphincter electromyography comprised of abnormal spontaneous activity, motor unit potentials (MUPs) more than 13 ms, polyphasic potentials more than 60%. MRI showed brain atrophy and the "hot cross bun" signal in the pontocerebellar degeneration.ConclusionMSA is a disorder characterized by progressive neuronal atrophy at certain sites of the central nervous system that control the urogenital function. MSA-related urological symptoms are analogous with symptoms of bladder outlet obstruction. It is necessary to take some reasonable investigations for avoiding misdiagnosis and unnecessary surgery.
