Synchronous papillary thyroid carcinoma with metastatic nasopharyngeal carcinoma issues regarding its diagnosis and management.
- Author:
Eliez Anne M. Dayanghirang
;
Ida Marie Tabangay-Lim
- Publication Type:Journal Article
- Keywords:
Case report;
double primary head and neck malignancy;
papillary thyroid;
nasopharyngeal cancer
- From:
Philippine Journal of Surgical Specialties
2020;75(2):148-154
- CountryPhilippines
- Language:English
-
Abstract:
A 46-year old female presented with a one-year history of a right lateral
neck mass which gradually increased in size and subsequently involved
bilateral cervical nodes. Diagnosed as Papillary Thyroid Carcinoma
Stage I (T1N2M0), she underwent Total Thyroidectomy, Central
Neck Dissection, Modified Radical Neck Dissection, Type I, right
and Modified Radical Neck Dissection Type III, left. Histopathology
revealed papillary thyroid carcinoma with no lymphovascular and
capsular invasion, and metastatic undifferentiated carcinoma in 15
out of 16 lymph nodes, probably nasopharyngeal in origin. Work
up uncovered an erythematous, friable nasopharyngeal mass. Its
histopathology was nasopharyngeal cancer, a second primary
malignancy. The malignancies were treated as separate entities. The
patient underwent chemoradiotherapy first for the nasopharyngeal
cancer. Radioactive Iodine for the thyroid malignancy was given
six months after completion of radiotherapy. Double primary
malignancies deserve aggressive treatment. The sequence of therapy
should be based on the severity of the malignancy.
- Full text:Synchronous papillary thyroid carcinoma.pdf