Susceptibility of Epilepsy in Rat with Cerebral Trauma
- VernacularTitle:脑外伤大鼠癫痫易感性的研究
- Author:
Yaxian DENG
;
Baoqin GAO
;
Weili YANG
- Publication Type:Journal Article
- Keywords:
traumatic brain injury, epilepsy, electroencephalograph (EEG), pentylenetetrazol (PTZ), susceptibility
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(3):231-232
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the susceptibility of epilepsy in rat with cerebral trauma. Methods An impact-acceleration head injury model was established with rats. After trauma, the electroencephalograph was recorded. Epileptic model wad established by injecting pentylenetetrazol (PTZ) intraperitoneally and the dosage of PTZ was recorded. Results The wave of delta and theta increased after trauma, alpha and beta decreased and there was significant difference among the power of delta, theta and alpha (P＜0.05). The dosage of rats with cerebral trauma was less than that in normal rats (P＜0.05). Conclusion The susceptibility of epilepsy in rat with cerebral trauma increases.
