Effect of Acupuncture on Expression of Neurofilament Protein in Neonatal Rats Injured Brain
- VernacularTitle:针刺对脑损伤仔鼠脑神经丝蛋白表达的影响
- Author:
Xiaojie LI
;
Rui SONG
;
Zhongren SUN
- Publication Type:Journal Article
- Keywords:
intrauterine infection, brain injury, acupuncture, neurofilament protein (NFP), hanging test
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(3):206-207
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of early acupuncture on the expression of neurofilament protein (NFP) in the brain and the neurobehavior of the neonatal rats with brain injury. Methods The pregnant Wistar rats were randomly divided into two groups: lipopolysaccharide (LPS) group and control group, which were consecutively injected intraperitoneally with LPS or saline. The full-term newborn rats from LPS group were randomly divided into acupuncture group and model group. Acupuncture group was acupunctured from postnatal 8 d. They were evaluated with hanging test, and the expression of NFP was detected with immunohistochemical stain 21 d after birth. Results Both the scores of hanging test and the expression of NFP were the highest in the control group, the lowest in the model group and medium in the acupuncture group (P<0.01). Conclusion Acupuncture may increase the expression of NFP and improve locomotor function of the neonatal rats with brain injury caused by intrauterine infection.
