Study on the Apoptosis of Rheumatoid Arthritis Synoviocyte Induced by Arsenic Trioxide
- VernacularTitle:三氧化二砷诱导类风湿关节炎滑膜细胞凋亡作用的研究
- Author:
Haozhe LV
;
Shiyu QIAO
;
Xiuli CHEN
- Publication Type:Journal Article
- Keywords:
arsenic trioxide, rheumatoid arthritis, fibroblast-like synoviocyte, apoptosis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(2):141-142
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the apoptosis of rheumatoid arthritis synoviocyte induced by arsenic trioxide.Methods Human rheumatoid arthritis fibroblast-like synoviocytes (HFLS-RA) were divided into control group and arsenic trioxide group. After 72 hours, pathology changes were observed and MTT tests were used to investigate apoptosis levels induced by arsenic trioxide.Results Arsenic trioxide can induce the apoptosis of rheumatoid arthritis synoviocyte, depending on time and dose.Conclusion Arsenic trioxide may induce apoptosis of rheumatoid arthritis synoviocyte.
