Application of cellular metabolomics in central nervous system diseases

VernacularTitle:细胞代谢组学及其在中枢神经系统疾病研究的应用进展
Author: Xiaoli HE ^{1
,

2} ; Yiwei SHI ² ; Hui WANG ² ; Jianying DAI ^{1
,

2} ; Zhanying HONG ^{1
,

2}
Author Information

1. School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China
2. School of Pharmacy, Naval Medical University, Shanghai 200433, China.
Keywords: cellular metabolomics; central nervous system diseases; cell model; biomarkers
From: Journal of Pharmaceutical Practice 2023;41(2):63-69
CountryChina
Language:Chinese
Abstract: Cell metabolomics is an important branch of metabolomics, which could dynamically monitor cell response and metabolic changes after drugs acting on cells, and look for potential biomarkers. Cell metabolomics has been widely used in illustration of disease mechanism, evaluation of drug efficacy and development of new drug through elucidating the pathophysiological mechanism of the disease and the effect of drug treatment intervention. The researches process of cellular metabolomics and its application in central nervous system diseases were reviewed in order to provide theoretical basis for in-depth study of the pathogenesis and prevention and treatment of central nervous system diseases.