Association between obesity phenotype and hypertension in middle-aged and elderly adults in China： a cohort study
10.19428/j.cnki.sjpm.2022.22258
- VernacularTitle:中国中老年人肥胖表型与高血压风险关联队列研究
- Author:
Yongfeng HU
1
;
Qiang LI
2
;
Liping LIU
1
;
Qiqiang HE
3
;
Gaolei LU
3
Author Information
1. Xinzhou District Center for Disease Control and Prevention, Wuhan, Hubei 431400, China
2. School of Nursing, Wuchang University of Technology, Wuhan, Hubei 430071, China
3. School of Public Health, Wuhan University, Wuhan, Hubei 430071, China
- Publication Type:Journal Article
- Keywords:
obesity phenotype;
middle-aged and elderly;
hypertension;
cohort study
- From:
Shanghai Journal of Preventive Medicine
2022;34(12):1197-1200
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the association between obesity phenotype and the occurrence of hypertension in middle-aged and elderly adults in China. MethodsData were obtained from the China Health and Retirement Longitudinal Study （CHARLS） in 2011 and 2015. Participants who completed two visits with ≥45 years old age at baseline were enrolled. Obesity phenotype was defined as the following four groups according to weight and metabolic status：metabolically healthy non-overweight/obesity （MHNO）， metabolically healthy overweight/obesity （MHO）， metabolically abnormal non-overweight/obesity （MANO）， and metabolically abnormal overweight/obesity （MAO）. Cox proportional risk regression model was used to analyze the relationship between obesity phenotype and the incidence of hypertension. ResultsA total of3 781 subjects with 1 775（46.95%） males and mean age of （57.76±8.57） years were included in this study. When the metabolically normal non-overweight/obese group （MHNO） was regarded as the reference group， the risk of developing hypertension was significantly increased （P<0.01） in MHO， MANO， and MAO with HRs of 1.35（1.11‒1.63）， 1.51（1.15‒1.97）， and 2.00（1.68‒2.38） respectively.ConclusionBoth MHO phenotype and MAO/MANO are significantly associated with the occurrence of hypertension in middle-aged and elderly adults.
