Clinical characteristics of 151 COVID-19 cases in a designated hospital in a district of Shanghai， 2022
10.19428/j.cnki.sjpm.2022.22263
- VernacularTitle:2022年上海市某区定点医院151例新型冠状病毒肺炎病例临床特征分析
- Author:
Wen ZHU
1
;
Hai ZHOU
1
;
Xiaoqing SHUAI
2
;
Lei CHENG
3
;
Chao WENG
1
Author Information
1. Shidong Hospital, Yangpu District (Shidong Hospital Affiliated to University of Shanghai for Science and Technology), Shanghai 200438, China
2. Le'an County People's Hospital, Fuzhou, Jiangxi 344300,China
3. Shanghai Pulmonary Hospital, Tongji University, Shanghai 200433, China
- Publication Type:Journal Article
- Keywords:
COVID-19;
designated hospital;
clinical characteristics;
cluster
- From:
Shanghai Journal of Preventive Medicine
2022;34(12):1180-1187
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the clinical characteristics of 151 local COVID-19 patients in Shanghai， 2022. MethodsThe clinical data of 151 COVID-19 patients admitted to a district-level designated hospital in Shanghai from April 13 to May 10， 2022 were reviewed， and their clinical manifestations， laboratory tests， lung imaging， treatment and outcomes were analyzed. ResultsThe 151 patients ranged from 3 to 97 years old， with a median age of 72 years. Most of them were clustered cases in the communities and families. The main clinical types were mild （95 cases， 62.9%） and general （47 cases， 31.1%）. Most of the 9 severe/critical patients （6.0%） were elderly and complicated with multiple comorbidities. The proportion of people who had not been vaccinated was as high as 66.9%， and the proportion of those among severe/critically ill patients who had not been vaccinated was even higher. The most common first symptoms were expectoration in 71 cases （47.0%）， fever in 51 cases （33.8%） and dry cough in 30 cases （19.9%）. The counts of white blood cells and neutrophils in mild or general group were mostly normal or decreased， and in the severe/critical group increased significantly （P<0.001）. Increase of troponin， D-dimer， creatinine， and myoglobin； and decrease of lymphocytes in severe/critical group were more common than the other clinical types （P<0.05）. The proportions of use of antibiotics， antiviral drugs， thymalfasin and heparin in severe/critical and general patients were significantly higher than those in mild patients （P<0.05）. Among the cured and discharged patients （138 cases， 91.4%）， the median number of days for COVID-19 viral nucleic acid to turn negative after treatment was 12 days. The negative conversion days of mild patients were significantly shorter than those of general patients and severe/critical patients （P<0.01）. Four （2.6%） death patients were all over 80 years old， unvaccinated， combined with multiple comorbidities， and eventually died of those serious comorbidities. ConclusionCOVID-19 patients at the district-level designated hospital are mainly clustered cases， and the proportion of patients who do not receive COVID-19 vaccine is high. Most of the hospitalized patients are mild， but advanced age， multiple underlying diseases， and lack of vaccination are high-risk factors for developing severe disease. Early assessment and comprehensive treatment are the key to improve prognosis.
