Relationship between Early Renal Injury and Pulse Pressure in Hypertension Patients
- VernacularTitle:脉压、脉压指数与原发性高血压肾损害早期的关系
- Author:
Shengxia ZHANG
;
Dongtai ZHAO
;
Xiaodong SONG
;
Weiping SHEN
- Publication Type:Journal Article
- Keywords:
hypertension, pulse pressure, pulse pressure index, renal injury
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(1):82-83
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between the early renal injury and the pulse pressure or pulse pressure index in hypertension patients. Methods The pulse pressure (PP) and the pulse pressure index (PPI) in 96 patients with mild to moderate essential hypertension were calculated and the urine β2-microglobulin (β2-MG), the urine α1-microglobulin (α1-MG), albumin were detected.Results The urine β2-MG, the urine α1-MG and albumin in patients with PP>65 mmHg were higher than those with PP≤65 mmHg （P<0.05）; The urine β2-MG and the α1-MG, albumin in patients with PPI>0.5 were higher than those with PPI≤0.5 （P<0.05）. While the patients with renal injury complicated with a higher PP or PPI than those without renal injury （P<0.05）. Conclusion The renal injury is more severe in patients with higher pulse pressure and pulse pressure index.
