A Case of Periumbilical Perforating Pseudoxanthoma Elasticum.

Author: Seo Rye YOO ¹ ; Min Sook JU ; Joo Yeon KO ; Young Suck RO
Author Information

1. Department of Dermatology, Hanyang University, College of Medicine, Seoul, Korea. romio@hanyang.ac.kr
Publication Type:Case Report
Keywords: Perforating pseudoxanthoma elasticum; Periumbilical
MeSH: Aged; Biopsy; Calcium; Elastic Tissue; Female; Humans; Pseudoxanthoma Elasticum*; Salts; Ulcer
From:Annals of Dermatology 2007;19(3):139-141
CountryRepublic of Korea
Language:English
Abstract: Periumbilical perforating pseudoxanthoma elasticum is a rare acquired disorder that usually occurs in obese, middle-aged, multiparous women. It is considered as a separate entity from the hereditary pseudoxanthoma elasticum due to lack of hereditary transmission and association with systemic disease. A 70-year-old multiparous woman presented with a 2-year history of a gradually enlarging, yellowish ulcerated plaque in the periumbilical region. The biopsy specimen showed irregularly altered elastic fibers with encrusted calcium salts that underwent transepidermal elimination. We report a rare case of periumbilical perforating pseudoxanthoma elasticum with no signs of hereditary pseudoxanthoma elasticum.