In Vitro Antibacterial Effect of a Mouthrinse Containing CPC (Cetylpyridinium Chloride), NaF and UDCA(ursodeoxycholic acid) against Major Periodontopathogens.
10.5051/jkape.1999.29.2.325
- Author:
Chong Kwan KIM
1
;
Bong Kyu CHOI
;
Yun Jung YOO
;
Sang Nyun KIM
;
Jae Kyun SEOK
;
Moon Moo KIM
Author Information
1. Department of Periodontology, Research Institute for Periodontal Regeneration, Dental College, Yonsei University, Korea.
- Publication Type:In Vitro ; Original Article
- Keywords:
Mouthrinse;
Cetylpyridinium chloride;
Periodontopathogens;
Maximum inhibitory dilutions(MID)
- MeSH:
Aggregatibacter actinomycetemcomitans;
Bacteria;
Bacteroides;
Cetylpyridinium;
Fusobacterium nucleatum;
Porphyromonas gingivalis;
Prevotella intermedia;
Treponema denticola
- From:The Journal of the Korean Academy of Periodontology
1999;29(2):325-332
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The antibacterial efficacy of a mouthrinse(Denta Gargle) containing CPC(cetylpyridinium chloride), NaF and UDCA(ursodeoxycholic acid), on major periodontopathogens, was in vitro examined and compared with that of Listerine by a broth dilution method. The bacteria tested were Actinobacillus actinomycetemcomitans, Bacteroides forsythus, Fusobacterium nucleatum subsp. vincentii, Prevotella intermedia, Porphyromonas gingivalis and Treponema denticola. The growth of all the bacteria were completely inhibited by a 1-min exposure to the both mouthrinses. When diluted at 1:5 or more, all bacteria analyzed but P. intermedia were not inhibited by Listerine. In contrast, Denta Gargle showed highly increased maximum inhibitory dilutions(MID) against all periodontopathogens included in this study, with MIDs ranging from 5-fold(F. nucleatum) to 160-fold dilutions(P. intermedia). The MIDs against A. actinomycetemcomitans, B. forsythus, P. gingivalis and T. denticola. were 1:40, 1:80, 1:80 and 1:80, respectively.
