Sural Nerve Morphometrics of Motor Neuron Disease
- VernacularTitle:运动神经元病的腓肠神经病理形态和定量分析
- Author:
Min XU
;
Cunjiang LI
;
Juexian SONG
;
Yan LU
;
Min WANG
;
Lu LIU
- Publication Type:Journal Article
- Keywords:
motor neuron disease, sural nerve, neuropathy, pathology
- From:
Chinese Journal of Rehabilitation Theory and Practice
2009;15(1):15-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathological features of sural nerve biopsy in patients with motor neuron disease （MND）. Methods 22 patients with amyotrophic lateral sclerosis (ALS) underwent sural nerve biopsy and routine electrophysiological examination. The transected images were captured and morphometrically analyzed.Results The myelinated fiber density decreased in ALS patients' sural nerves, and larger fibers were involved mostly. The thinly myelinated fibers increased. Conclusion The sural nerves of ALS patients shows mild but definite pathological changes.
