Radiotherapy Result of Brain Stem Tumors.
- Author:
II Han KIM
1
;
Mi Gyoung YANG
;
Charn Il PARK
Author Information
1. Department of Therapeutic Radkology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Brain stem tumor;
Radiotherapy;
Clinical response;
Survival
- MeSH:
Brain Stem Neoplasms*;
Brain Stem*;
Brain*;
Cranial Nerves;
Diagnosis;
Drug Therapy;
Humans;
Magnetic Resonance Imaging;
Neurologic Manifestations;
Radiotherapy*;
Survival Rate
- From:Journal of the Korean Society for Therapeutic Radiology
1989;7(2):189-196
- CountryRepublic of Korea
- Language:English
-
Abstract:
Twenty five patients with tumors of the brain stem were treated with radiotherapy between 1979 and 1987. Histological diagnosis could be obtained in 6 cases, and other 19 patients were diagnosed by neurologic findings and CT or MRI. Eighteen patients were treated by radical radiotherapy and 6 patients received both operation and radiotherapy, while 1 patient received chemotherapy after radiotherapy. Total dose ranged from 50 Gy to 55 Gy. By an clinical scoring scale at 2 months after radiotherapy, no complete response was obtained, but 16 cases achieved partial response, 2 cases were stable, and 4 cases were deteriorated. The overall survival rate at 3 years was 36%. Age, performance status at diagnosis, degree of cranial nerve involvement, CT pattern of post-contrast enhancement, and clinical response by scoring scale were correlated with survival.