Establishment and application of path-based management mode of 5-HT3 receptor antagonists in chemotherapy patients
- VernacularTitle:化疗患者5-羟色胺3受体拮抗剂路径化管理模式的建立与应用
- Author:
Lu GAO
1
;
Jing LI
1
;
Xiao ZHOU
1
;
Yuan HUANG
1
;
Lin YU
1
;
Huizhu SONG
1
;
Yuhua YANG
1
Author Information
1. Wuxi People’s Hospital Affiliated to Nanjing Medical University，Jiangsu Wuxi 214023，China
- Publication Type:Journal Article
- Keywords:
5-hydroxytryptamine-3 receptor antagonist;
chemotherapy patients;
path-based management;
informatization
- From:
China Pharmacy
2023;34(4):493-496
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To establish the path-based management mode of 5-hydroxytryptamine-3 receptor antagonist （5- HT3RA） in chemotherapy patients， and to improve the rationality of medication in chemotherapy patients. METHODS 5-HT3RA standardized drug use control rules were formulated， with the help of medical intelligence and decision support （MINDS） system， path-based management was carried out for chemotherapy patients using 5-HT3RA in the form of whole-process information capture and prescription pre-review， and whole-process intervention was implemented on medication indications， usage and dosage， course of treatment， etc. The intervention effect was analyzed by comparing the changes in the use of 5-HT3RA without indication， unreasonable usage and dosage， repeated medication， unreasonable course of treatment， and per capita drug cost before and after the implementation of path-based management. RESULTS A total of 9 181 patients were included. After the implementation of path- based management， the proportion of unindicated drugs decreased by 0.48%， and the rate of unreasonable single dosage， unreasonable frequency， repeated medication， unreasonable treatment course （5-HT3RA still used 3 days after chemotherapy） decreased by 10.48%， 0.65%， 1.33% and 0.34%； per capita cost of 5-HT3RA decreased by 13.72 yuan； there were statistical significance （P＜0.05）. CONCLUSIONS 5-HT3RA path-based management mode effectively improves the rationality of medication and provides a new idea for rational clinical drug use.
