Mean Hematocrit values, disease severity, and discharge status of undernourished versus well-nourished children with Dengue Infection in a tertiary government hospital
https://doi.org/10.56964/pidspj20222302009
- Author:
Kiara Natalie B. Roble
1
;
Robert A. Tagocon
1
Author Information
1. Northern Mindanao Medical Center
- Publication Type:Journal Article
- MeSH:
Dengue;
Malnutrition;
Hematocrit
- From:
Pediatric Infectious Disease Society of the Philippines Journal
2022;23(2):64-70
- CountryPhilippines
- Language:English
-
Abstract:
Background:Studies comparing hematocrit values, disease severity, and discharge status between well-nourished and undernourished pediatric dengue patients are limited.
Objective:This study compared the mean hematocrit values, disease severity and discharge status of undernourished vs. well-nourished pediatric dengue patients admitted in a tertiary government hospital.
Methodology:A retrospective cohort study involving 114 pediatric dengue patients, with comparison groups of well-nourished and undernourished children matched according to age, phase of illness and sex was done. Main outcomes measured were mean hematocrit values, disease severity and discharge status.
Results:There was a significantly lower mean pre-resuscitation hematocrit in the wasted (M=39.67%, SD=3.78) compared to the well-nourished group (M=43.68%, SD=4.72), p=0.006, among children >6 to 12 years old in the febrile phase. There were no significant differences in disease severity and discharge status between wasted and well-nourished children. In those >2 to 6 years old in the febrile phase, the severely wasted had significantly higher pre-resuscitation hematocrit (M=43.28%, SD=4.77) compared to well-nourished children (M=39.11%, SD=5.34), p=0.041. More severe dengue, worse discharge status and an earlier time to demise was seen among severely wasted children.
Conclusion:Wasted participants had significantly lower mean hematocrit values with no difference in diseaseseverity and discharge status when compared to well-nourished participants. Severely wasted children had significantly higher hematocrit values, severe dengue, and worse discharge status.
- Full text:009_PIDSP-vol-23-no-2_ROBLE_HCT.pdf
