Effect of Recombinant Human Granulocyte Colony-Stimulating Factor on Acute Cerebral Infarction: 74 Cases Report
- VernacularTitle:重组人粒细胞集落刺激因子治疗急性脑梗死74例疗效观察
- Author:
Ping DU
;
Jiawei ZHANG
;
Haijun WANG
;
Tieyan WANG
- Publication Type:Journal Article
- Keywords:
cerebral infarction, bone marrow stem cells, recombinant humangranulocyte colony-stimulating factor (G-CSF)
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(9):809-810
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect of recombinant human granulocyte colony-stimulating factor (rhG-CSF) on acute cerebral infarction.Methods74 patients with acute cerebral infarction were divided into treatment and control groups. Two groups were treated by conventional methods of acute cerebral infarction; the treatment group was treated with rhG-CSF additionally. The two groups were measured before and 3 months after treatment by China Stroke Scale (CSS), respectively. Meanwhile, the side effect of rhG-CSF was observed during treatment.ResultsCSS score was better in the treatment group than in the control group 3 months after treatment (P<0.05). No side effect occurred in the treatment group.ConclusionrhG-CSF is safe and effective to treat acute cerebral infarction.