Effect of Early Rehabilitation on Inflammatory Response after Acute Cerebral Infarction
- VernacularTitle:早期康复介入对急性脑梗死炎症反应的影响
- Author:
Zhaoru GAN
;
Lihua SHI
;
Chaoqun CAI
;
Zhiguang XIE
;
Yingmei XU
;
Haipeng LIU
;
Linan SANG
- Publication Type:Journal Article
- Keywords:
acute cerebral infarction, early rehabilitation, high-sensitivity C-reactive protein, interleukin-1, interleukin-6, neurological function
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(9):807-808
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the effect of early rehabilitation on motor function, high-sensitivity C-reactive protein (hs-CRP), interleukin-1（IL-1） and interleukin-6（IL-6） in patients with acute cerebral infarction (ACI). Methods160 patients with ACI were randomly divided into rehabilitation group (n=80) and control group (n=80), who accepted early rehabilitation and routine medicine or medicine only, respectively. They were assessed with modified Edinburgh-Scandinavian Stroke Scale (MESSS) and their peripheral level of hs-CRP, IL-1 and IL-6 were detected before and 1, 2, 4, and 8 weeks after treatment. Results4 and 8 weeks after treatment, the level of hs-CRP, IL-1 and IL-6 were lower in rehabilitation group than in control group（P＜0.05）, as well as the scores of the MESSS （P＜0.01）. The incidence of improvement is more in rehabilitation group than in control group（P＜0.05）. ConclusionEarly rehabilitation can reduce the expression of hs-CRP, IL-1 and IL-6, and improve the neurological function in patients with ACI.
