Clinical profile and course on follow-up of newborns of SARS-CoV-2 positive mothers
https://doi.org/10.56964/pidspj20222301006
- Author:
Vivien Lorraine L. Duyongco
1
;
Victora G. Bael
1
;
Karen Joy N. Kimseng
1
;
Cleo Anna Marie D. Pasco
1
;
Aimee Cristine C. Tan
1
Author Information
1. Chong Hua Hospital Mandaue
- Publication Type:Journal Article
- Keywords:
Maternal COVID-19 infection (SARS-CoV-2 positive mother);
Neonatal outcome;
Long-term follow-up
- MeSH:
SARS-CoV-2
- From:
Pediatric Infectious Disease Society of the Philippines Journal
2022;23(1):27-38
- CountryPhilippines
- Language:English
-
Abstract:
Objective:This study aims to determine the clinical profile and course on follow-up of newborns delivered to a SARS-CoV-2 positive mother from two private tertiary hospitals.
Methodology:This is a retrospective, cross-sectional study. A chart review of all neonates delivered to SARS-CoV-2 positive mothers was conducted. Subsequent interview was done to determine their clinical course and neurologic status at 3-, 6-, 9-, 12-, and 15-month-old. Data collected was presented as frequencies, percentages, or proportions.
Results:Out of the 67 newborns born to SARS-CoV-2 positive mothers, three neonates tested positive for SARS-CoV-2. All three were delivered to mothers with mild symptoms, were full term, with good APGAR score and appropriate for gestational age. One was eventually intubated and managed as COVID-19 confirmed critical. Among the SARS-CoV-2 negative newborns, majority had an unremarkable neonatal outcome. Thirty-six neonates were available for follow-up: 1 expired due to aspiration pneumonia at 2 months of age, 4 were readmitted for pneumonia, UTI, acute gastroenteritis, and cow’s milk allergy. Twenty-one had infection at one point prior to this study follow-up but were all mild not requiring admission. Two had abnormal head size, while 2 had developmental delay, these 4 infants with neurological findings on follow-up were all RT-PCR negative at birth.
Conclusion:Maternal COVID-19 infection does not necessarily result to a neonatal infection. For those neonate swith mild symptoms, SARS-CoV-2 causality could not be established. On follow-up, there were a few who developed significant problems that have long-term implications in the overall growth and development of the child.
- Full text:006_PIDSP-vol-23-no-1_DUYONGCO_-covid-ffup.pdf
