Ambient dose equivalent in 99mTcO4- single photon emission computed tomography of the thyroid among patients with hyperthyroidism
10.19485/j.cnki.issn2096-5087.2023.02.015
- Author:
Jun HU
;
Hao LIU
;
Yanqin SHI
;
Suying YU
;
Chao DOU
;
Lan ZHAO
;
Feifei WANG
;
Mengjie DONG
- Publication Type:Journal Article
- Keywords:
hyperthyroidism;
single photon emission computed tomography;
radiation protection;
dose equivalent rate
- From:
Journal of Preventive Medicine
2023;35(2):152-154
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the changes of ambient dose equivalent rate in 99mTcO4- single photon emission computed tomography (SPECT) of the thyroid among patients with hyperthyroidism, so as to provide insights into radiation protection guidance.
Methods:Patients with hyperthyroidism who underwent 99mTcO4- SPECT of the thyroid in a tertiary hospital were enrolled. The ambient dose equivalent rate was measured at different time points following 99mTcO4- infection and at sites with different distances from patients' neck, and the effects of time post-injection, distance from patients' neck, 24-hour thyroidal radioiodine uptake and thyroid weight on the ambient dose equivalent rate were examined using a generalized linear mixed model.
Results:Totally 100 patients with hyperthyroidism were enrolled, including 24 men and 76 women and with a mean age of (38.5±14.0) years. The generalized linear mixed model was statistically significant (F=6 610.165, P<0.001), and patients' thyroid weight, time post-injection and distance from patients' neck significantly affected the ambient dose equivalent rate (F=57.967, 15 988.574, 11 200.645, all P<0.001), and the ambient dose equivalent rate positively correlated with patients' thyroid weight and negatively correlated with time post-injection and distance from patients' neck.
Conclusions:The ambient dose equivalent rate is affected by patients' thyroid weight, time post-injection and distance from patients' neck among patients with hyperthyroidism undergoing 99mTcO4- SPECT of the thyroid. Delay in contact with patients or keeping distance from patients may be effective for radiation protection.
- Full text:甲亢患者99mTcO4-甲状腺SPECT检查的周围剂量当量率分析.pdf