Outcomes of infants born to mothers with SARS-CoV-2 infection in a tertiary hospital
https://doi.org/10.56964/pidspj2021220106
- Author:
Jemilly Margaux L. Po
1
;
Marimel R. Pagcatipunan
1
Author Information
1. University of the Philippines - Philippine General Hospital Department of Pediatrics Division of Infectious and Tropical Diseases
- Publication Type:Journal Article
- Keywords:
Vertical transmission
- MeSH:
COVID-19;
Infant, Newborn
- From:
Pediatric Infectious Disease Society of the Philippines Journal
2021;22(1):40-50
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:Pregnant women are a susceptible population to emerging infections. Recent published data have shown evidence of possible transplacental transmission of SARS-CoV-2. However, at present there are not enough data to determine its effect on the fetus. This study aims to determine the outcomes of infants born to mothers with SARS-CoV-2 infection.
Methods:A retrospective descriptive institution-based study using data collected from medical records of infants born to confirmed COVID-19 mothers delivered from April to June 2020.
Results:Of the 47 neonates, none of them were positive for SARS-CoV-2 RT-PCR. Majority were born full-term, mean gestational age of 37 weeks, weight of 2867 grams, appropriate for gestational age, good APGAR score, and delivered through cesarean section. Symptomatic neonates (27.7%) had tachypnea and vomiting as the most common manifestation, 13.3% had lymphopenia while pneumonia was the predominant radiologic finding. There was a significant association between the presence or absence of symptoms among mothers and neonates (p=0.037).
Conclusion:The neonatal outcome in this study was good with 98% survival at 2 weeks of life. There was note of 2.1% morbidity and mortality. Given that the clinical data in newborns are very limited and the possibility of a vertical transmission is still uncertain, it is crucial to closely monitor neonates with increased risk of COVID-19 infection.
- Full text:06-Vol-22-No-1_Po_Outcomes-of-Infants-Born-to-Mothers-with-SARS-CoV-2-Infection-in-a-Tertiary-Hospital_FORMATTED_v5.pdf
