Use of combination of Oral Levothyroxine and Liothyronine in severe Hypothyroidism with Massive Pericardial Effusion
https://doi.org/10.15605/jafes.037.02.17
- Author:
Poh Shean Wong
1
;
Sue Wen Lim
2
;
Chin Voon Tong
1
;
Masni Mohamad
2
;
Zanariah Hussein
2
Author Information
1. Endocrinology Unit, Department of Medicine, Hospital Melaka, Malaysia
2. Endocrinology Unit, Department of Medicine, Hospital Putrajaya, Malaysia
- Publication Type:Other Types
- Keywords:
Hypothyroid
- MeSH:
Pericardial Effusion;
Thyroxine;
Triiodothyronine
- From:
Journal of the ASEAN Federation of Endocrine Societies
2022;37(2):106-112
- CountryPhilippines
- Language:English
-
Abstract:
Thyroid hormone plays an important role in cardiovascular function. Pericardial effusions are commonly seen in cases of severe hypothyroidism. However, large to massive pericardial effusions with cardiac tamponade are exceptionally rare. Herein, we present two cases of severe hypothyroidism with massive pericardial effusion. Our first case demonstrates that a patient with large pericardial effusion can be managed conservatively with aggressive thyroid hormone replacement therapy. In our second case, pericardiocentesis was performed in addition to thyroid hormone replacement therapy as the underlying aetiology of effusion could not be reasonably limited to hypothyroidism. These two cases served to highlight and demonstrate rapid normalisation of thyroid function test by using aggressive oral thyroid hormone replacement therapy using liothyronine, in combination with levothyroxine, which led to resolution of pericardial effusion and prevent its re-accumulation.
- Full text:1875-Article Text-21573-1-10-20221125.pdf
