Treatment outcome of a β-hCG Secreting Intracranial Germ Cell Tumorin an adult Filipino using definitive Chemotherapy followed by Radiotherapy: A case report
https://doi.org/10.15605/jafes.037.01.12
- Author:
Florence Rochelle Gan
1
;
Maria Honolina Gomez
1
;
Julie Ann Tapispisan
2
Author Information
1. Section of Endocrinology, Diabetes and Metabolism, University of Santo Tomas Hospital, Manila, Philippines
2. Section of Oncology, University of Santo Tomas Hospital, Manila, Philippines
- Publication Type:Case Reports
- Keywords:
β‑hCG
- MeSH:
Neoplasms, Germ Cell and Embryonal;
Germinoma;
Hypopituitarism;
Diabetes Insipidus
- From:
Journal of the ASEAN Federation of Endocrine Societies
2022;37(1):97-102
- CountryPhilippines
- Language:English
-
Abstract:
We report a case of a 24-year-old Filipino male who complained of general weakness, polydipsia, weight loss, bitemporal headaches, loss of libido and behavioral changes. Endocrine work-up revealed neurogenic diabetes insipidus and panhypopituitarism. Brain MRI showed multiple intracranial tumors in the left frontal lobe, pineal and suprasellar region with moderate non-communicating hydrocephalus. Intracranial mass biopsy with ventriculo-peritoneal shunting was done. Histopathology of the mass and CSF revealed a germinoma. He underwent chemoradiotherapy while on maintenance hormone replacement.
- Full text:1259-Article Text-18245-2-10-20220529.pdf
