Outcomes of surgical sperm retrieval for non-obstructive azoospermia: A single-center experience.
- Author:
Alvin Christopher D. Lavadia
1
;
Dennis G. Lusaya
2
;
Nikko J. Magsanoc
3
;
Virgilio M. Novero Jr.
4
Author Information
- Publication Type:Journal Article
- Keywords: Non-obstructive azoospermia; surgical sperm retrieval; male infertility; testicular sperm extraction (TESE); micro-TESE
- From: Philippine Journal of Urology 2022;32(2):43-49
- CountryPhilippines
- Language:English
-
Abstract:
INTRODUCTION:To evaluate the sperm retrieval rate and factors influencing its success among patients
who undergo conventional or microsurgical testicular sperm extraction (TESE) for non-obstructive
azoospermia.
METHODS:Data were from 223 consecutive patients who underwent conventional or microsurgical TESE from August 2011 to January 2021 under two urologists of the center. Data regarding age, follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone, estradiol, testicular size, histopathology, surgical technique, and sperm retrieval were collected. Patients with obstructive azoospermia, repeated TESE procedure, and those who underwent TESE for oncofertility were excluded. Using simple logistic regression analysis, the relationship of the different factors to successful sperm retrieval was computed as odds ratio.
RESULTS:The overall surgical sperm retrieval rate was found to be 65.71%. The odds ratio of successful sperm retrieval were 1.04 (95% CI 1.00-1.09) for age, 0.94 (95% CI 0.91-0.97) for FSH, 0.93 (95% CI 0.87-0.99) for LH, 1.24 (95% CI 0.99-1.55) for testosterone, and 0.93 (95% CI 0.88-0.98) for estradiol. Decreased testicular size was also associated significantly with lower sperm retrieval rate (OR 0.22, 95% CI 0.09-0.56). Histopathologic pattern and surgical technique were also significantly associated with successful sperm retrieval.
CONCLUSION:The surgical sperm retrieval rate in this institution is comparable to the global surgical sperm retrieval rate. Age, FSH, LH, estradiol, testicular size, histopathologic pattern and surgical technique were found to have significant association to successful surgical sperm retrieval. - Full text:The surgical sperm retrieval rate.pdf
