Image-guided Strategy of Intensity-modulated Radiotherapy in Helical Tomography for Nasopharyngeal Carcinoma
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2023.0118
- VernacularTitle:鼻咽癌螺旋断层调强放疗图像引导策略
- Author:
Meng-xue HE
1
;
Pei-xun XU
1
;
Hong HUANG
1
;
Xuan-guang CHEN
1
;
Hui-lang HE
1
;
Zi-xian ZHANG
1
;
Hui LIU
1
;
Sen-kui XU
1
;
Wen-yan YAO
1
Author Information
1. State Key Laboratory of Oncology in South China， Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy， Sun Yat-sen University Cancer Center， Guangzhou510060，China
- Publication Type:Journal Article
- Keywords:
nasopharyngeal carcinoma;
HT;
image-guided radiotherapy;
setup error
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2023;44(1):131-137
- CountryChina
- Language:English
-
Abstract:
ObjectiveThis study aimed to analyze the difference in setup error before and after correction of systematic error. To determine the most appropriate image-guided strategy during HT treatment， we use different scanning ranges and image-guidance frequencies in patients with nasopharyngeal carcinoma （NPC） treated with helical tomotherapy （HT）. MethodsFifteen patients with NPC who received HT treatment in Sun Yat-sen University Cancer Center from October 2019 to February 2020 were selected. Megavoltage computed tomography （MVCT） scanning was performed before each treatment. After five times of radiotherapy， system-error correction was performed to adjust the setup center. The setup errors before and after the correction of systematic errors， as well as the setup errors of different scanning ranges and different scanning frequencies， were collected for analysis and comparison. ResultsWhen comparing the setup errors before and after the correction of systematic error， the differences in setup errors in the left–right （LR）， superior–inferior （SI）， and anterior–posterior （AP） directions were statistically significant （P<0.05）.The different scanning ranges of "nasopharynx + neck" and "nasopharynx" were compared， and a statistically significant difference was found in yaw rotational errors （P<0.05）. In the comparison of daily and weekly scan frequency after system-error correction， a significant difference was found in AP direction （P<0.05）. ConclusionDuring radiotherapy for NPC， the systematic error can be corrected according to the first five setup errors， and then small-scale scanning was selected for image-guided radiotherapy every day.
