The Role of Exosomes in Force-Related Periodontal Inflammatory Response
10.16156/j.1004-7220.2022.02.28
- VernacularTitle:外泌体在力相关牙周炎症反应中的作用
- Author:
Yifan ZHANG
1
,
2
,
3
,
4
,
5
;
Chun XU
1
,
2
,
3
,
4
,
5
Author Information
1. Department of Prosthodontics, Shanghai Ninth People’ s Hospital, Shanghai Jiao Tong University School of Medicine
2. College of Stomatology, Shanghai Jiao Tong University
3. National Center for Stomatology
4. National Clinical Research Center for Oral Diseases
5. Shanghai Key Laboratory of Stomatology
- Publication Type:Journal Article
- Keywords:
exosomes;
mechanical loading;
periodontium;
inflammation
- From:
Journal of Medical Biomechanics
2022;37(2):E369-E373
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are extracellular vesicles secreted by cells with a variety of molecular components, which can play the role of substance transport and signal communication between cells through autocrine and paracrine. Exosomes exist widely in vivo and participate in many physiological and pathological processes, including force-related periodontal inflammation. There are stress receptor cells in the periodontium, which can sense force loading on the tooth. An appropriate amount of mechanical loading can maintain health of the periodontium, while excessive mechanical loading may cause destruction and absorption of the periodontium, leading to periodontal inflammation. This article reviews the role of exosomes in force-related inflammation response, especially in periodontal inflammation response.
