Study on odor composition change of traditional Chinese medicine sachet during placement based on ultra-fast gasphase electronic nose technology
- VernacularTitle:基于超快速气相电子鼻技术研究中药香囊放置过程中的气味成分变化
- Author:
Xiaocong YU
1
;
Lixin ZHANG
1
;
Zekun WANG
1
;
Yachun SHU
1
;
Xianlin ZHANG
1
;
Yi YAO
1
;
Chunqin MAO
2
Author Information
1. Dept. of Pharmacy,the Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China
2. College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine sachet;
electronic nose;
gas chromatography;
odor composition;
material basis
- From:
China Pharmacy
2023;34(3):339-344
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the odor composition changes of two kinds of traditional Chinese medicine sachet (children type and adults type) with different placement time by using ultra-fast gasphase electronic nose technology. METHODS The change rule of sachet components at different storage times was analyzed by gas chromatography. At the same time, the qualitative results were obtained by combining electronic nose with Arochembase database. Discriminant factor analysis was used to analyze the overall odor composition differences of the two sachet samples. RESULTS A total of 10 odor compositions were identified in children-type sachet, including α-pinene and β-pinene as the functional index compositions; five odor compositions of children-type sachet disappeared after 0.25 days, and most of them disappeared after 7 days; the cumulative contribution rate of discriminant factor analysis was 99.225%. A total of 8 odor compositions were identified in adult-type sachets, including α-pinene and α-phellandrene as the functional index compositions; four odor components disappeared after the adult-type sachet was placed for 0.25 days; after 15 days of placement, the peak 6-8 disappeared, and the intensity of peak 5 decreased by 34.3% compared with 0 day of placement; the cumulative contribution rate of discriminant factor analysis was 91.965%. CONCLUSIONS With the extension of storage time, the smell and composition of the two traditional Chinese medicine sachets are decreasing. It is recommended that the use time of children-type sachet is 7 days, and that of adult-type sachet is 15 days.