Inhibition of Urine 11-dH-TXB2 by Dihydroxyaluminum Aminoacetate-Heavy Magnesium Carbonate-Aspirin: A Long-term Result
- VernacularTitle:铝镁匹林对尿11-脱氢血栓素B2影响的长期观察
- Author:
Yan HUANG
;
Chaomei FAN
;
Yang WANG
;
Yiling HUANG
;
Li WANG
;
Wenyan Bian
;
Yishi LI
- Publication Type:Journal Article
- Keywords:
aspirin, platelet aggregation, 11-dH-TXB2
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(7):670-671
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the inhibition of urine 11-dH-TXB2 by dihydroxyaluminum aminoacetate-heavy magnesium carbonate-aspirin in Chinese cardiovascular patients after long-term therapy. Methods103 cardiovascular patients were treated with oral doses of dihydroxyaluminum aminoacetate-heavy magnesium carbonate-aspirin tablets (162 mg aspirin) daily for 24 weeks. The Urine 11-dH-TXB2 concentration were measured before and 6, 12, 24 weeks after administration. ResultsThe urine 11-dH-TXB2 concentration were （1840.41±1452.63） pg/ml, （820.01±610.55） pg/ml, （1011.19±1148.12） pg/ml, （1290.82±1425.51） pg/ml before and 6, 12, 24 weeks after administration. The urine 11-dh-TXB2 concentration was higher in 24th week than in 12th weeks and 6th week. ConclusionThe dihydroxyaluminum aminoacetate-heavy magnesium carbonate-aspirin can inhibit the platelet aggregation, which decreased after long-term administration.
