Simultaneous occurrence of Papillary Carcinoma and Medullary Carcinoma
https://doi.org/10.15605/jafes.034.02.16
- Author:
Lyza Camille Gadong
1
;
Thelma Crisostomo
1
Author Information
1. Section of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Makati Medical Center, Philippines
- Publication Type:Case Reports
- Keywords:
Medullary thyroid cancer
- MeSH:
Thyroid Neoplasms;
Thyroid Cancer, Papillary
- From:
Journal of the ASEAN Federation of Endocrine Societies
2019;34(2):226-228
- CountryPhilippines
- Language:English
-
Abstract:
The cell origin, histopathologic features, and prognosis of medullary and papillary thyroid carcinoma are different and to have them occur simultaneously in a single patient is a rare occurrence. This is a case of a 38-year-old female who presented with an enlarging anterior neck mass whose fine needle aspiration biopsy could not rule out a papillary lesion. Thus, she was advised to undergo total thyroidectomy, and her final histopath showed a simultaneous medullary and papillary thyroid carcinoma. Her initial serum calcitonin was elevated at 252 pg/ ml, and it remained persistently elevated over the course of 7 months. A repeat ultrasound revealed solid nodules with coarse calcifications and enlarged lymph nodes at both submandibular regions. This warranted a repeat surgery with neck dissection with the finding of eight lymph nodes positive for metastatic carcinoma. On follow up after her second surgery, the calcitonin decreased to 42.70 pg/ml. Knowledge of this simultaneous occurrence of medullary thyroid carcinoma and papillary cancer is important for its prognostic implications and therapeutic plan
- Full text:589-Article Text-8573-1-10-20191112.pdf
