Self-reported Hypoglycemia in insulin-treated patients with Diabetes: Results from the Philippine Cohort of the International Operations Hypoglycemia Assessment Tool (IO HAT) study
https://doi.org/10.15605/jafes.033.01.03
- Author:
Roberto Mirasol
1
;
Nemencio Nicodemus Jr.
2
;
Anand Jain
3
;
Dr. Arvind Vilas Gadekar
4
;
Susan Yu-Gan
5
Author Information
1. Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, St. Lukes Medical Center, Quezon City
2. Department of Biochemistry, University of the Philippines Manila
3. Novo Nordisk Healthcare AG, Zurich, Switzerland
4. Novo Nordisk Pharma Operations (BAOS) Sdn. Bhd, Kuala Lumpur, Malaysia
5. Metropolitan Medical Centre in Manila, Philippines
- Publication Type:Journal Article
- Keywords:
International Operations Hypoglycemia Assessment Tool;
Insulin-treated patients with diabetes
- MeSH:
Hypoglycemia;
Philippines
- From:
Journal of the ASEAN Federation of Endocrine Societies
2018;33(1):12-21
- CountryPhilippines
- Language:English
-
Abstract:
Objective:To determine the frequency of hypoglycemia in insulin-treated patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in the non-interventional International Operations Hypoglycemia Assessment Tool (IO HAT) study.
Methodology:This sub-analysis included Filipino patients with T1DM or T2DM, aged 18 years and older, treated with insulin for more than 12 months, who completed the two-part self-assessment questionnaires (SAQ1 and SAQ2) and patient diaries that recorded hypoglycemia during retrospective (6 months/4 weeks before baseline) and prospective period (4 weeks after baseline (ClinicalTrials.gov number: NCT02306681).
Results:A total of 671 patients were enrolled and completed the SAQ1 (62 patients with T1DM and 609 patients with T2DM). Almost all patients (100% in T1DM and 99.3% in T2DM) experienced at least 1 hypoglycemic event prospectively. The incidence of any hypoglycemia was also high in the prospective period compared to retrospective period (72.6 [95% CI: 64.8, 80.9] events PPY and 43.6 [95% CI: 37.8, 49.9] events PPY; p=0.001, respectively) in T1DM patients.
Conclusion:Among insulin-treated patients, higher rates of hypoglycemia were reported prospectively than retrospectively. This indicates that the patients in real-life setting often under-report hypoglycemia. Patient education can help in accurate reporting and appropriate management of hypoglycemia and diabetes.
- Full text:429-Article.pdf
