Findings in Positron Emission Tomography of Brain in Rats with Syndrome of Stagnation of Liver-Qi
- VernacularTitle:肝气郁结模型大鼠正电子发射脑功能成像研究
- Author:
Ziwang LIU
;
Haibin ZHAO
;
Xiujing ZHANG
;
Baoci SHAN
;
Hua LIU
;
Lijuan HE
- Publication Type:Journal Article
- Keywords:
Stagnation of Liver-qi Syndrome, rats, positron emission tomography, cerebral function
- From:
Chinese Journal of Rehabilitation Theory and Practice
2011;17(9):837-839
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of brain function in rats with Stagnation of Liver-qi Syndrome. Methods Model ofStagnation of Liver-qi was made with chronic stress combined with isolated raising in 10 normal Wistar rats. They were scanned with positronemission tomography (PET) before and after modeling. Data analysis was carried out using SPM (statistical parametric mapping 2) inMATLAB software. Results After modeling, the glucose metabolism decreased (P<0.001) in left frontal lobe, parietal lobe, hypothalamus;bilateral posterior cingulate; right anterior cingulate, while the glucose metabolism increased (P<0.001) in left parahippocampal gyrus, insula,temporal lobe, frontal lobe; right basal ganglia, thalamus. Conclusion The function of some cerebral areas can be changed undergoingStagnation of Liver-qi Syndrome.