Impact of Antiepileptic Drugs on Cognitive Function of Epilepsy Patients
- VernacularTitle:抗癫痫药对癫痫患者认知功能的影响
- Author:
Wei SUN
;
Wei MAO
;
Yuping WANG
;
Weiwei WANG
;
Xun WU
- Publication Type:Journal Article
- Keywords:
epilepsy, Topiramate, Valproate, cognition, Wechsler Adult Intelligence Scale
- From:
Chinese Journal of Rehabilitation Theory and Practice
2010;16(7):648-649
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the cognitive impairment in epilepsy patients with Topiramate (TPM) or Valproate (VPA) treatment by using WAIS-CR. Methods30 untreated epilepsy patients were divided into two groups receiving TPM or VPA, respectively. All the patients were examined with WAIS-CR before and 3 months after treatment. ResultsThe IQ of TPM group decreased 3 months after treatment (P<0.05). ConclusionTPM may impair the cognitive function in epileptics reflected by decreased IQ.
