Effect of Rehabilitation on Long-term Efficacy of Botulinum Toxin Type A on Spastic Cerebral Palsy
- VernacularTitle:康复训练对A型肉毒毒素治疗痉挛型脑瘫长期疗效的影响
- Author:
Jianjun LIU
;
Shurong JI
;
Weihong WU
;
Yan ZHANG
;
Fanyong ZENG
;
Nanling LI
- Publication Type:Journal Article
- Keywords:
cerebral palsy, spasticity, Botulinum toxin type A, long-term efficacy, nerve block, rehabilitation
- From:
Chinese Journal of Rehabilitation Theory and Practice
2011;17(7):654-656
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the long-term efficacy of Botulinum toxin type A (BTX-A) on spasticity in cerebral palsy, and theeffect of rehabilitation on it. Methods 230 children with spastic cerebral palsy were treated with BTX-A block. The dose of BTX-A wasidentified with the weight of the children and the Modified Ashworth Scale (MAS). They were divided into group A who exercised morethan 2 h/d, and group B who exercised less than 2 h/d or not. They were assessed with Gross Motor Function Measure (GMFM) 1 year aftertreatment. Results There was no significant difference between group A and B with ages, weight, MAS, GMFM before block (P>0.05), norwith BTX-A effect time (P>0.05). The GMFM improved significantly in both group A and B 1 year after block (P<0.05), and it improvedmore in group A than group B (P<0.01). Conclusion The long-term efficacy of BTX-A block is positive. The rehabilitation training afterblock can help children to improve their gross motor function.
