Incidence trends and associated factors of diabetes mellitus in Korean children and adolescents: a retrospective cohort study in Busan and Gyeongnam.
10.6065/apem.2015.20.4.206
- Author:
Jung Hyun LEE
1
;
Yu Mi KIM
;
Min Jung KWAK
;
Su Yung KIM
;
Hyun Ji KIM
;
Chong Kun CHEON
;
Woo Yeong CHUNG
;
Im Jeong CHOI
;
Su Young HONG
;
Hee Won CHUEH
;
Jae Ho YOO
Author Information
1. Department of Pediatrics, Kosin University Gospel Hospital, Kosin University College of Medicine, Busan, Korea.
- Publication Type:Original Article
- Keywords:
Diabetes;
Korea;
Incidence;
Child;
Adolescent
- MeSH:
Adolescent*;
Busan*;
Child*;
Cohort Studies*;
Diabetes Mellitus*;
Diabetes Mellitus, Type 2;
Female;
Hospitals, General;
Humans;
Incidence*;
Korea;
Male;
Medical Records;
Retrospective Studies*
- From:Annals of Pediatric Endocrinology & Metabolism
2015;20(4):206-212
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study investigated the incidence trends and associated factors of type 1 (T1DM) and type 2 diabetes mellitus (T2DM) in children and adolescents under 15 years of age in Busan and Gyeongnam, Korea from 2001 to 2010. METHODS: Medical records of newly diagnosed diabetes patients (n=328; 160 males, 168 females) were collected in questionnaire form from 5 tertiary and 42 general hospitals in Busan and Gyeongnam. RESULTS: The average crude incidence rate of T1DM and T2DM was 2.01/100,000 (95% confidence interval [CI], 1.76-2.28) and 0.75/100,000 (95% CI, 0.60-0.92), respectively. The incidence rate ratio (IRR) of T1DM was 1.31 (95% CI, 1.01-1.69), and that of T2DM was 1.97 (95% CI, 1.25-3.11) in the latter half-decade (2006 to 2010) compared to the early half-decade (2001 to 2005). There were gradually increasing incidence trends in both T1DM and T2DM over the 10-year period (P for trend: T1DM, 0.0009; T2DM, <0.0001). Age-specific IRR was highest in the 10- to 14-year-old group, regardless of diabetes type. In particular, a rapid increase in incidence of T2DM occurred in the 10- to 14-year-old group. IRR for females was 1.07 (95% CI, 0.83-1.38) for T1DM and 1.56 (95% CI, 1.01-2.41) for T2DM. IRR for Busan (urban) was 1.41 (95% CI, 1.09-1.83) for T1DM and 1.49 (95% CI, 0.96-2.30) for T2DM. CONCLUSION: T1DM and T2DM incidence both increased over time in youth under age 15 living in Busan and Gyeongnam; in particular, the incidence of T2DM in adolescents increased more rapidly.
